Cy Young (1867)
Duff Cooley (1873)
Bill Dietrich (1910)
Tommy Holmes (1917)
Ferris Fain (1921)
Denny McLain (1944)
Bill Castro (1952)
Tom Hume (1953)
Domingo Ramos (1958)
Mike Kingery (1961)
Billy Beane (1962)
Laz Diaz (1963)
Eric Gunderson (1966)
Brian Jordan (1967)
Alex Ochoa (1972)
Danny Kolb (1975)
Pat Light (1991)
Laz Diaz has been a major league umpire since 1999.
Danny Kolb was drafted by Minnesota in the seventeenth round in 1993, but did not sign.